Molecular Trigger for Epilepsy Sudden Death
A gene that is most common in a syndrome associated with abnormal heart rhythms and sudden death, triggers epileptic seizures and could explain sudden unexplained death in epilepsy reported researchers from Baylor College of Medicine.
This particular potassium channel “KvLQT,” that has been identified in neurons of the central nervous system, gives scientists a clue to which epilepsy patients face the greatest risk of dying unexpectedly, according to Dr. Jeffrey Noebels. 
Originally the channel had been discovered in heart muscle cells but now, for the first time, it has been identified in the brain or nerve cells.
“Idiopathic (unexplained) epilepsy is one of neurology’s oldest mysteries. While most people with epilepsy will have a normal lifespan, our finding now points the way to a simple and essential test to identify risk for sudden death in persons with seizures of unknown origin. In these patients, a routine cardiology evaluation consisting of an EK and, if indicated, a genetic screening test for this family of genes can positively identify this new risk factor,” said Noebels. “If the gene test is positive, there are effective treatments for the heart irregularity, including drugs known as beta blockers, as well as the use of a cardiac pacemaker to prevent lethal arrhythmias.”
Eighteen percent of deaths come suddenly and without warning in epilepsy, devastating families. To read the full article and learn more visit medicalnewstoday.com